AI Lab in Rome
since February 2026
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Arcano Zero

Every journey starts from zero.

We build artificial intelligence products for health, education, research, law and industry. With people at the centre and technology at their service.

0 Why we are called this

In the tarot, Arcanum Zero is the Fool.

He has no number, because he can stand anywhere: at the beginning, at the end, outside the deck. He is the traveller who sets off with a bundle, a dog at his side and the courage to take the first step into the unknown.

That is how we work. Every product starts from zero: from a real problem, a specific person, a simple question. Which problem can we solve today with tomorrow’s technology?

We are a lab that doesn’t stop at the slides. We design, build and bring to market our own products, with Italian intellectual property.

I The manifesto

  1. We are small. It is our advantage: nobody has told us yet what is impossible.
  2. The best technology is not a privilege. It must reach everyone, first those who need it most.
  3. We don’t build AI that replaces people. We build AI that makes them extraordinary.
  4. A child who reads again. A patient who understands. A founder who takes off. That is how the world changes.
  5. We do in months what others do in years. And we don’t wait for permission.
  6. We start from Rome. We think for the world.

Think huge.
Stay human.

Pensa in grande. Resta umano.

II The arcana

Eleven products, each born from a specific problem.

Tap a card to flip it and see where we stand.

On the lab table, still face down: NewsLens, news read across languages and compared; Sirena, an AI voice for small businesses; Block by Block, civic participation for cities.
Every product, one page each

III What we do

Three crafts that feed each other.

Our products

Vertical AI platforms built around specific needs. Each can become a startup in its own right, spin-offs included.

  • SaaS, licences, white label
  • Regulated sectors: healthcare, legal, minors’ data, critical infrastructure
  • Explainability and GDPR designed in from the start

Arcano Consulting

We take companies and startups from the plan to the capital needed to make it real.

  • Industrial and business plans
  • Investor decks and financial models
  • Public funding: regional, national and European grants
  • AI adoption in your processes

Custom AI and digital

We build for others with the same method we use for ourselves.

  • Turnkey AI applications and agents
  • Websites, apps and interactive experiences
  • Arcano Marketing: content, social, branded games
All services in detail

The method, from idea to market

The same path for every product, whether ours or a client’s. A lean team, multiplied by artificial intelligence across the whole cycle.

01 / 05

IV The figures

Few people, a great many products.

Alessandra Marziali

Founder and CEO

Creative producer and product builder, MA in Digital Media Arts, university lecturer. She leads product and AI architecture across the whole portfolio.

Stefano Liardo

Innovation and funding

Partner and Innovation Manager. Public funding and structural funds, LUISS graduate.

Loretta Mura

Operations and administration

Over thirty years in established energy and plant engineering companies: administration, compliance, processes.

Francesco Mancuso

Technical infrastructure

Mission-critical systems in telecommunications, data centres and healthcare.

Dania Mogiani

Communication and relations

Communication, social media and community; client relations and executive support.

The guardians

The advisory board: universities, research and clinical practice at our side.

  • Prof. Giancarlo D’AmbrosioProfessor of General Surgery, Sapienza University of Rome
  • Prof. Carlo Maria MedagliaIUL University, delegate for Third Mission, Digital Innovation and Artificial Intelligence
  • Prof. Marco MaiuroSapienza University of Rome, president of the CASAM Foundation
  • Dr Luigi MossaOrthopaedics, traumatology and sports medicine
  • Dr Maria Giulia LoretiNutritional biologist, University of Perugia
  • Dr Michela CaramutaGeneral surgery, nutrition and aesthetic medicine
Full bios of the team and advisors

V The oracle

Ask the deck a question.

A three-card reading with the 22 major arcana, reinterpreted for innovation. Ironic, but not too much: there is always practical advice at the end.

> write a question, then shuffle the deck

  1. 01 / your strength
  2. 02 / the opportunity
  3. 03 / the next move

VI Contact

The first step is yours.

Tell us about a problem, an idea, a grant not to miss. We reply within two working days.

Email
info@arcanozero.it
Office
Via Alessandro Torlonia 16, Rome, Italy

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